UTERUS

UTERUS

FERTILIZATION

FERTILIZATION

CLITORIS

CLITORIS

UTERUS

UTERUS
The uterus (Latin: uterus) is the female reproductive organ of humans. In this text, you will read all about the uterus and its functions. Anatomy of the Uterus The most important function of the uterus, is to accept a fertilized embryo which implants into its lining. After implantation, the embryo will develop into a fetus and it will stay inside the uterus until birth. The human uterus consists of two segments, being: The body of the uterus (Latin: corpus uteri). This is the largest part of the uterus and is also where the implantation of the embryo takes place. This part of the uterus is also connected to the fallopian tubes. The cervix (Latin: cervix uteri; often abbreviated as cervix). The cervix consists of the neck of the cervix and the ectocervix (often referred to as the ‘portio’). The ectocervix is visible and palpable inside the vagina and is therefore also the connection with the vagina. De portio (the ectocervix) is lined with squamous epithelium, the endocervical canal with mucus producing glandular epithelium. The shape of the uterus The human uterus is pear shaped. Yet the shape of the uterus varies from organism to organism. For instance, animals that generally bear more than one young have two uterine horns (cornua uteri), one left and one right. This way, each uterine horn can harbour one or more young. The size of the uterus of an adult woman is about 5 to 10 centimetres. The uterus of a woman who has never been pregnant before is about the size of a mandarin. After the first pregnancy (and birth) the uterus is slightly bigger. During pregnancy, the uterus will expand and become heavier. The uterus of a pregnant woman can reach a weight of a kilogram. This weight does not include the placenta, amniotic fluid and fetus. When the woman hits menopause, the uterus will shrink slightly. Position of the Uterus The uterus lies deep in the abdomen. To be more precise, the uterus lies within the pelvic diaphragm, directly behind the bladder and in front of the rectum. There are several ligaments that hold the uterus in place. The broad ligament (ligamentum latum) and the round ligament (ligamentum rotondum) are the most important ligaments. What does the uterine wall consist of The uterine wall consists largley of smooth muscle tissue. This layer is called the myometrium. During labour, this smooth muscle tissue will contract (contractions) in order to push the baby out of the body. Just like any organ in the human body, the uterus also needs blood. This blood is supplied by two uterine arteries. The Latin names of these arteries are aa. uteria. These arteries are situated on the left and on the right of the uterus. The endometrium The endometrium is also referred to as the uterine lining and it lines the entire uterine cavity. The endometrium reacts strongly to two female hormones, estrogen and progesterone. Under the influence of estrogen, the uterine lining becomes thicker. The hormone progesterone stimulates the production of more mucus glands. Once the progesterone levels drop (there is less progesterone to be found in the body), the mature and thick uterine lining can no longer stay intact and it must leave the body. When the uterine lining leaves the body through the vagina, we call this menstruation. What many people don't know, is that the endometrium consists of two layers, namely the: Basal layer (lamina basalis). This basal layer always remains present inside the uterus. Functional layer (lamina functionalis). This layer is shed during menstruation and will build up again from the basal layer. Abnormalities and diseases of the uterus There are several abnormalities and diseases that can occur in the uterus. The following abnormalities and diseases may occur in the uterus: Inflammation of the endometrium (endometritis). Polyps Hyperplasia Uterine Cancer Fibroids Malignant tumor Trophoblast abnormalities Cervix polyp Warts Extropion Endometriosis Cervical Cancer Examination of the uterus There are several reasons why an examination of the uterus may be necessary. For example, a woman who consults her GP due to specific symptoms, if a woman is pregnant, or if a woman needs to be examined for uterine cancer. Examination of the uterus can be done in several ways, the method used depends on the reason for the examination. The uterus can be examined in the following ways: Vaginal examination Speculum examination Ultrasound Hysteroscopy Laparoscopy The uterus and the orgasm When a woman is sexually aroused, the uterus will erect slightly. The uterus is pulled in an upward direction, making the vagina slightly longer. When a women has an orgasm, the pelvic muscles and the uterine muscle contract. There are women who barely feel the contraction of the uterine muscle, but there are also women who find that these contractions produce a very pleasant feeling. When the woman has had an orgasm, it can take up to ten minutes before the uterus has returned to its normal position. The Cervix The cervix (also referred to as the cervix uteri) is the narrow, cylindrical portion of the uterus. One end of the cervix protrudes into the top end of the vagina, and the other end is continuous with the corpus uteri. The inside of the cervix is lined with columnar epithelium. In the vagina, the cervix has an opening referred to as the external os (ostium externum). When one looks into the vagina, the part of the cervix that is visible is referred to as the 'portio'. Usually, (excluding during the ovulation) the uterus is blocked by a thick impermeable mucus. This mucosal plug can be found inside the cervix, and it protects the uterus against all kinds of infections. When a woman is pregnant, the cervix dilates shortly before labor. During the dilation of the cervix, the mucosal plug will come out (often accompanied by some blood). This is usually a signal that labor is about to commence. During the menstrual cycle, the cervix undergoes a few changes. Just after menstruation, the cervix is closed and positioned relatively low. In the period leading up to ovulation, the cervix rises, and the structure becomes softer. In this period, the cervix also opens slightly. After the ovulation, the cervix will return to its low position and the opening will close again. Cervical Cancer Cervical cancer is relatively common amongst women and is caused by an infection of Human Papillomavirus (abb. HPV). Cervical cancer can be detected at an early stage by examining a smear (via vaginal examination). If cervical cancer is detected at an early stage, treatment is effective and the woman is likely to be cured of this type of cancer.

Saturday 1 October 2011

KIDNEY & URETHERS

The Kidneys The kidneys (L. renes) lie in the paravertebral gutters, at the level of L12 to L3 vertebrae. Their long axes are almost parallel with
the axis of the body. The ureter runs inferiorly from each kidney and passes over the pelvic brim at the bifurcation of the common iliac artery. This runs along the lateral wall of the pelvis and enters the urinary bladder. The kidneys' functions are: 1. The removal of excess water, salts and products of protein metabolism; 2. The maintenance of pH; 3. Production and release of erythopoietin, which controls blood cell production; 4. Synthesis and release of renin to influence blood pressure; 5. And the production of 1,25- hydroxycholecalciferol (activated for of vitamin D) for control of calcium
metabolism. Back to top Position, Form, and Size of the Kidneys Click here for a diagram of the position of the kidney from the posterior aspect. Each kidney lies in a mass of perirenal (perinephric) fat, posterior to the peritoneum (i.e., it is retroperitoneal), on the posterior abdominal wall. These lie alongside the vertebral column,
against the psoas major. The superior parts of the kidneys are protected by the thoracic cage and are
tilted so that their superior poles are nearer to the median plane than their inferior poles. The right kidney lies at a slightly lower level than the left one. This is due to the large size of the right lobe of the liver. Each kidney has anterior and posterior surfaces, medial and lateral margins (borders), and superior and inferior poles. The lateral margin is convex. The medial margin is indented or concave where the renal sinus and renal pelvis are located. Kidneys are about: 1. 10-11 cm in length; 2. 5-6 cm in width; 3. 2.5-3 cm in thickness; 4. They weigh about 135-150 grams; 5. The left kidney is often slightly longer than the right one. Each kidney is ovoid in outline. Its indented medial margin gives it a somewhat bean-shaped appearance. At this concave part of each kidney is a vertical cleft, the renal hilum (hilus). Here, the renal artery enters and the renal vein and renal pelvis leave the kidney. The hilum leads into a space within the kidney called the renal sinus, which is about 2.5 cm deep. The renal sinus is occupied by the renal pelvis, renal calices, renal vessels and nerves, and varying amounts of fat. From anterior to posterior are the: 1. Renal vein 2. Renal artery 3. Renal pelvis Back to top Surface Anatomy and Markings of the
Kidneys In thin adults with poorly developed abdominal muscles, the inferior pole of the right kidney is usually palpable in the right lateral region. It is a firm, smooth, somewhat rounded mass that descends during inspiration. The normal left kidney is not usually palpable. The levels of the kidneys change during respiration and with changes in posture. Each kidney moves about 3 cm in a vertical direction during the movements of the diaphragm that occurs with deep breathing. The hilum of the left kidney lies in the transpyloric plane, about 5 cm from the median plane. This plane cuts through the superior part of the right kidney. From the posterior aspect of the kidney (important for surgery), the inferior pole of the right kidney is about a fingerbreadth superior to the iliac crest and that its superior pole is superior to the 12th rib. Gross Structure of the Kidneys Click here for a diagram of the gross structure of the kidneys. The Fibrous Capsule Each kidney is invested in a strong, fibrous capsule. It passes over the lips of the hilum to line the renal sinus and become continuous with the walls of the calices. The kidney and its capsule are
surrounded by pararenal fat, but it is sparse on its anterior surface. This fat is less dense and thus an outline of the kidney is usually visible in radiographs, CTs and MRIs. The Renal Pelvis This is continuous inferiorly with the ureter. It is surrounded by fat, vessels and nerves in the renal sinus. The word pelvis is derived from the
Greek word pyelos, meaning basin. Within the renal sinus, the renal pelvis usually divides into two wide, cup- shaped major calices (G. flower cups). Each major calyx (calix) is subdivided into 7 to 14 minor calices. The urine empties into a minor calyx from the collecting tubules that pierce the tip of the renal papilla obliquely. It then passes through the major calyx, renal pelvis, and the ureter to enter the urinary bladder. Back to top Renal Fascia and Renal Fat Each kidney, invested by the fibrous renal capsule, is also embedded in a substantial mass of perirenal fat that constitutes the fatty renal capsule. Very little fat lies anterior to the kidney. The fatty renal capsule is in turn covered by fibroareolar tissue called the renal fascia. This fascia encloses the kidney, its surrounding fibrous and fatty capsules, and the suprarenal (adrenal) glands. These covering help to maintain the
position of these organs. Superiorly, the renal fascia is continuous with the fascia on the inferior surface of
the diaphragm (the diaphragmatic fascia). Medially, the anterior layers of the fascia on the right and left sides blend with each other anterior to the abdominal aorta and inferior vena cava. The posterior layer of renal fascia fuses medially with the fascia over the psoas major muscle. The layers of renal fascia are loosely united inferiorly and may easily be separated. The encasement of the kidney in fat is an important factor in anchoring it in position. The extraperitoneal fat, the pararenal fat is located between the peritoneum of the posterior abdominal wall and the renal fascia. Relations of the Kidneys (Ashwell) Anterior Posterior Left
Kidney Spleen Stomach Suprarenal gland Pancreas Small intestine
(duodenum, jejunum and ileum) Left colic flexure
Splenic artery
Splenic vessels 11th and 12th ribs Diaphragm Quadratus
lumborum
Transversus
abdominis
Psoas major Subcostal vessels
Subcostal nerves
Iliohypogastric
nerve
Ilioinguinal nerve Right
Kidney Right suprarenal gland Right lobe of liver Right colic flexure Small intestine
Duodenum As for left except no 11th rib For the anterior relations of the left kidney, it is composed of 7 "S": 1. Suprarenal; 2. Splenic; 3. Stomach (gastric part); 4. Splenic vessels; 5. Sweetbread (the pancreas); 6. Small intestine (duodenum, ileum and
jejunum); 7. Splenic flexure (or left colic flexure). Back to top Blood Supply of the Kidney Renal Arteries Click here to go to the renal arteries under "The Blood Vessels of the Abdomen
and Pelvis." This arises from the aorta below the level of the superior mesenteric artery. Each renal artery gives off one or more inferior suprarenal arteries and branches that supply the perirenal tissue, renal capsule, pelvis and the proximal part of the ureter. Accessory renal arteries are common (30% of individuals). They usually arise above or below the
main renal artery and follow the hilum. Segmental Arteries Near the hilum each artery divides into anterior and posterior divisions, which in turn divide into segmental arteries. These supply the 5 renal vascular segments (apical, superior (anterior), inferior, middle (anterior) and posterior). Each vascular segment is supplied by end arteries, i.e., there are no anastomoses. The initial branches of the segmental
arteries are lobar, usually one to each pyramid. However, before entry they subdivide into 2 or 3 interlobar arteries. At the junction of the cortex and medulla, each interlobar artery divides into arcuate arteries. These diverge at right angles. Interlobular arteries diverge from the arcuate arteries to ascend into the cortex, to give rise to the glomerular arteries. Venous Drainage of the Kidneys Click here to go to the "Blood Vessels of the Abdomen and Pelvis." The renal veins drain into the IVC. The left renal vein is longer than the right renal vein and receives the left suprarenal veins and left gonadal vein. On the right, these drain directly into the IVC. Back to top Renal Innervation Click here to go to "The Nerves and Lymphatics of the Abdomen and Pelvis." The renal plexus is formed from the rami from the: 1. The coeliac ganglion and plexus; 2. The aorticorenal ganglion; 3. The lower thoracic splanchnic nerves; 4. The 1st lumbar splanchnic nerve; 5. And the aortic plexus. The plexus usually continues into the kidney around the renal arteries. Most renal nerves are vasomotor. Sensory nerves pass back to the CNS with the thoracic splanchnic nerves. The renal plexus gives rise to the ureteric and gonadal plexuses. Lymphatic Drainage of the Kidneys This is to the lumbar nodes. Back to top The Ureters These are thick-walled, expandable muscular ducts with a narrow lumen. They carry urine from the kidneys to the urinary bladder. As urine passes along the ureters, peristaltic waves occur in their walls. Each ureter is continuous above with the funnel-shaped renal pelvis. The Abdominal Ureter The abdominal part of the ureter is about 12.5 cm long and 5 mm wide. This closely adheres to the parietal peritoneum and is retroperitoneal throughout its entire course. It descends almost vertically, anterior to the psoas major muscle. As the right ureter descends, it is closely related to the IVC, the lumbar lymph nodes and the sympathetic trunk. The ureter crosses the brim of the pelvis and the external iliac artery, just beyond the bifurcation of the common iliac artery. The Pelvic Ureter This part of the ureter course posteroinferiorly on the lateral wall of the pelvis, external to the parietal peritoneum and anterior to the internal iliac arteries. They continue to a point about 1.5 cm superior to the ischial spines. Each ureter then curves anteromedially, superior to the levator ani muscle, where it is closely adherent to the peritoneum. The ureters pass obliquely through the bladder wall. When the bladder distends, the ureters are compressed and flattened, thus preventing regurgitation of urine and the chance of ascending infections. The narrowest parts of the bladder are at the pelviureteric region, when it begins. It is also narrow along the intramural course in the bladder. Furthermore, the ureter may kink at the pelvic brim. At these sites, there is the likelihood of
impaction of ureteric stones. In the Male In the male, the only structure that passes between the ureter and the peritoneum is the ductus deferens. The ureter lies lateral to this duct and enters the posterosuperior angle of the bladder, just superior to the seminal vesicle. In the Female In the female, the ureter descends on the lateral wall of the pelvis minor. Here it forms the posterior boundary of the ovarian fossa. As it descends, the ureter passes medial to the origin of the uterine artery. It continues to the level of the ischial spine. Here it is crosses superiorly by the uterine artery. It passes close to the lateral part of the fornix of the vagina, especially on the left side. Like in the male, the ureter enters the bladder at the posterosuperior angle. Back to top Blood Supply of the Ureters Click here to go to "The Blood Supply of the Abdomen and Pelvis." The blood supply is from the following
arteries: 1. The renal; 2. The abdominal aorta; 3. The gonadal; 4. The common iliac; 5. The internal iliac; 6. And the vesical and uterine arteries. Depending on the part of the ureter,
there is a different arterial supply. There are good longitudinal anastomoses between these vessels. The venous drainage follows a similar pattern to arterial supply. Innervation of the Ureters Click here to go to "The Innervation and Lymphatic Supply to the Abdomen and
Pelvis." This is through the ureteric plexus, which is derived from the renal, aortic, superior and inferior hypogastric plexuses. Ureteric supply is these is derived from- 1. Sympathetic: T10-12, L1; 2. Parasympathetic: S2-4. Afferent pain fibres pass back to T11, T12 and L1. Ureteric pain is severe and spasmodic (renal colic) and is referred to the groin, labia majora, scrotum and anterior thigh.

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